We are sorry, but we are unable to process your request because JavaScript have been disabled!
CLICK HERE when cookies and javascript will be enabled!

We are sorry, but we are unable to process your request because Cookies have been disabled!
CLICK HERE when cookies and javascript will be enabled!


Product Catalog


Tretiva Brand, bought today 261


Tretiva® is a medication developed to treat severe forms acne. This is a retinoid treatment with very potent keratolytic and comedolytic properties. Tretiva® capsules are formulated for the use in adults and children over 12 years of age.  Show full description

Shipping Options
  • Air Mail
  • ems
Active ingredientsOther names for this medicationSimilar Products


$1.40 per capsule


$42.00 per 30 capsules

Air Mail$20.00


$1.21 per capsule


$72.45 per 60 capsules

Air Mail$20.00


Order now

Save $11.55

$1.16 per capsule


$103.95 per 90 capsules

Air Mail$20.00


Order now

Save $22.05

120 capsules

$1.10 per capsule


$132.30 per 120 capsules

Air Mail$20.00


Order now

Save $35.70

240 capsules

$1.00 per capsule


$239.40 per 240 capsules

Air Mail$20.00


Order now

Save $96.60

270 capsules

$0.95 per capsule


$255.15 per 270 capsules

Air Mail$20.00


Order now

Save $122.85

360 capsules

$0.89 per capsule


$321.30 per 360 capsules

Air Mail FREE


Order now

Save $182.70


Tretiva® is manufactured by Intas Pharmaceuticals. This is an oral retinoid in the capsule form. Tretiva® is formulated specifically for severe forms of acne, such as recalcitrant nodular acne, acne conglobata, and acne fulminans. The active ingredient of Tretiva® is Isotretinoin, a first-generation retinoid and derivative of vitamin A.


- severe acne vulgaris (cystic, nodulocystic or recalcitrant nodular acne), characterized by red painful bumps, cysts, nodules with a diameter of 5 mm or greater, and painful lesions beneath the skin. It occurs if skin produces too much sebum and pores get clogged, as the acne-causing bacteria P. acnes (Propionibacterium acnes) proliferate inside of a clogged pore.

- acne conglobata, characterized by abscesses and draining sinus tracts in addition to nodulocystic acne symptoms.

- acne fulminans, that develops after an unsuccessful treatment of acne conglobata and is much harder to treat due to its unresponsiveness to the variety of medications.

MOA (mechanism of action):

Isotretinoin is a potent comedolytic, keratolityc, sebostatic, and anti-inflammatory agent. It fights acne by making skin less oily and normalizing follicular keratinization (dead epithelial cells built up in the pores). It reduces the size of sebaceous glands (microscopic organs producing skin oil) so it produces less sebum, while removing the residue of old skin cells from the pores. By these actions Isotretinoin indirectly reduces the amount of P. acnes in the skin.


Tretiva® capsules are swallowed whole and taken with food.

The treatment duration is between 16-24 weeks depending on the severity of condition and tolerance.

The daily intake should be divided in two doses.

For adults and children over 12 years:

The recommended starting dose: 0,5-1,0 mg per kg of body weight a day. After a few weeks the dose should be adjusted by the doctor.

For patients with severe kidney problems: 10 mg a day. After a few weeks the dose should be adjusted by the doctor.

For severe skin condition: 2,0 mg per kg of body weight a day as tolerated.


Never exceed the doctor’s recommended dose.

Do not adjust the dose without your doctor’s approval.

Do not take your daily dose of Tretiva® at once.

If you notice any of the more serious side effects, stop taking Tretiva® immediately and seek medical advice.

Women of child-bearing potential must not get pregnant 1 month before starting the Tretiva® treatment course, during it, and 1 month after stopping the course.

Your acne may get worse during the first week of the Tretiva® treatment course. This does not mean you should stop taking Tretiva®. Your skin condition will most likely improve with continuous treatment.

If your acne has not improved after 4-6 weeks of the Tretiva® treatment course, seek medical advice.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not apply a double dose.


Do not exceed the doctor's recommended dose. The symptoms of Tretiva® overdose may include vomiting, facial flushing, cheilosis, abdominal pain, headache, dizziness, and ataxia. If any of these occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately.


Store at a room temperature from 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away the tube after the expiration date. Keep away from children.

Order now

Side effects

The most common side effects associated with the use of Tretiva® are:

  • dry skin
  • chapped lips
  • dry eyes
  • dry nose and nosebleeds

Less common but much more serious side effects of Tretiva® are:

  • serious allergic reactions (hives, difficulty breathing, swelling of the face or mouth, fever, rash)
  • mental health problems (depression, psychosis, etc.)
  • brain problems (bad headache, blurred vision, dizziness, nausea or vomiting, seizures, stroke)
  • abdomen problems (severe stomach, chest or bowel pain, trouble swallowing, heartburn, diarrhea, rectal bleeding, yellowing of your skin or eyes, dark urine)
  • bone and muscle problems (back pain, joint pain, muscle weakness, broken bone)
  • hearing and vision problems
  • blood sugar problems
  • raise of fats and cholesterol in blood

Side effects occurrence does not only depend on the medication you are using, but also on your overall health and other factors.


Do not take Tretiva® if you are allergic to Isotretinoin.

Do not take Tretiva® if you have a history of severe allergic reactions associated with the use of retinoids or vitamin A.

Do not take Tretiva® if you are allergic to any of the other ingredients comprised in Tretiva®.

Do not take Tretiva® if you are allergic to peanut or soya.

Do not take Tretiva® if you have mental problems, asthma, liver disease, diabetes, heart disease, osteoporosis or eating disorder (anorexia nervosa).

Do not take Tretiva® if you are taking any acne medications (benzoyl peroxide, adapalene, sulfur, salicylic acid), antihistamines (azelastine), Vitamin A, corticosteroids (fluticasone, beclomethasone), antibiotics (clindamycin, erythromycin, tetracyclines), antipruritics (cholestyramine), diarrhea drugs (colestipol), obesity drugs (orlistat), photosensitizing agents (porfimer, verteporfin), antidepressants (hypericum perforatum) or anticoagulant (warfarin).

Do not take Tretiva® for mild or moderate acne.

Tretiva® is strictly prohibited in women who are pregnant, plan to have a baby or are breastfeeding.

Do not use Tretiva® in patients under 12 years of age.

Do not drive or operate machinery at night while using Tretiva®, as it decreases night vision.

Do not take Tretiva® if you have very high levels of cholesterol or triglycerides in your blood.

Do not take Tretiva® if you are overweight or addicted to alcohol.

Do not take Tretiva® if you have hypervitaminosis A.

Order now

Frequently asked questions

Q: What Tretiva® is used for?

A: Tretiva® is used to treat severe acne vulgaris, acne conglobata, and acne fulminans.

Q: Is Tretiva® safe for teenagers?

A: Tretiva® is considerably safe for the use in patients over 12 years of age, as long as used for prescribed condition and at prescribed doses.

Q: Can Tretiva® be used in pregnant women?

A: Tretiva® is strictly prohibited in women who are pregnant, plan to have a baby or breastfeeding.

Order now

Target PointShipping MethodTrackingDelivery TimePrice

Worldwide Shipping

  Not trackable14-21 business days$20.00 per order
  Trackable, where available5-9 business days$30.00 per order

Delivery time is:

Registered Mail - 14-21 business days price - $20.00, no signature is required on delivery.
EMS - 5-9 business days price - $30.00, signature is required on delivery.
Your order will be packed safe and secure and dispatched within 24 hours.

This is exactly how your parcel will look like (pictures of a real shipping item). It has a look of a regular private letter and does not disclose its contents. Size - 9.4x4.3x0.3 inches (24x11x0.7cm).

Order now

What are people saying about the Canadian Pharmacy?

With so much fraud on the internet, I wasn’t sure you were not one of them. I decided to take a risk and ordered Cialis Soft. CP did an amazing job helping me on each stage until my order arrives, including phone consulting and helping to choose the most appropriate delivery and payment methods. I Wholeheartedly recommend you as «the full package deal» - a team of professionals! – Wilson Leroy

I have tried both Viagra and Cialis. Both have their pros and cons. I get a better and more consistent erection with Viagra. It started working after about 30 mins and it really carries on for a good 24 hrs. I get occasional headaches from Viagra, but the result is definitely well worth it! – Martin Moore

I'm 65 and I suffered ED after a heart attack. I decided to try Viagra. I started from min dosage 25mg. All I can say is that it works extremely well for me. Mild flushing in my face but certainly not bothersome. Very pleased! – Jonathan Harris

I was very skeptical, but did ended up getting Viagra Super Active. I can't recommend these pills enough. I feel like a man all over again. Thank you! – Henry Petersen

I’m grateful for sending me your catalogue. I want to compliment you on the excellent ED meds you provide. It was certainly worth the money and enabled me to satisfy my lover. As a result, I have regular sex life and happier marriage. – Kevin Durand

Thank you so much on the excellent job!! I made an order on February 4th. I also paid for the fast ship 3 to 5 days delivery. I haven't got any problems with that. All meds were delivered in time, with no damages. Definitely will buy more meds from you!!! – Phil Doherty

Canadian Pharmacy is quite simply the best drug store I've been offered in a very long time. I initially went to the doctor for ED and found out I had diabetes. I have ordered Cialis on and off for the past year and it works great within 30-60 min. More than appropriate price for the enjoyment! Great deal! – Paul Robinson